Count Cells Without Slides
Watch the video to see how much plastic waste has been reduced by scientists using CellDrop Automated Cell Counters around the world.
Reduce plastic waste, eliminate disposable slide costs, and automate cell counting in your lab with DeNovix CellDrop Automated Cell Counters.
DeNovix patented DirectPipette™ technology replaces hemocytometers and plastic slides traditionally used in cell counting equipment. The CellDrop is the only automated cell counter that eliminates the costs and plastic waste associated with cell counting slides.
Automate counts, eliminate costs, and reduce plastic waste in your cell counting workflow.
Brightfield – 3 seconds
Dual Fluorescence – 8.5 seconds
No recalibration required for the life of the instrument.
Trust in the reproducibility of your results with CellDrop’s patented sample chamber design.
Load cell suspension into sample chamber. Sample can be loaded from either side of the arm.
Press the Count button, and let the CellDrop do the work! Count data will appear in 3–8 seconds.
After wiping the surfaces with a dry lab wipe, the CellDrop is ready for the next sample.
The CellDrop software excels in a wide variety of applications. View CellDrop technical notes to learn more.
Primary Cells
Tissue Culture
Isolated Nuclei
GFP
Yeast
Protoplasts
Pollen
Algae Cells
Insect Cells
The CellDrop’s innovative design improves efficiency and sustainability in cell counting equipment by removing the need for plastic slides. Scientists around the world have prevented millions of plastic slides from being disposed of by counting cells without slides.
The CellDrop has achieved ACT® Label certification from My Green Lab®, making it the first automated cell counter accredited by the program. The ACT Environmental Impact Factor Label provides a third-party verification for the environmental impact of laboratory products.
Watch the video to see how much plastic waste has been reduced by scientists using CellDrop Automated Cell Counters around the world.
No slides = less plastic waste and less money spent on consumables.
Models: Automated Brightfield and Fluorescence
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Brightfield
Rapid and reliable for tissue culture counts and viability measurements. Widely used for samples with low or no debris present.
Brightfield, Trypan Blue, Primary Trypan Blue, Nuclei Trypan Blue
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Dual Fluorescence & Brightfield
Improve the accuracy of counts and viability measurements, even with challenging samples. Dual fluorescence optics and assays such as AO/PI (Acridine Orange / Propidium Iodide) combine to eliminate subjectivity and reliably identify live and dead cells.
Brightfield, Trypan Blue, Primary Trypan Blue, AO/PI, AO, PI, Primary AO/PI, GFP, Yeast, Custom Apps, Nuclei Trypan Blue, Nuclei AO/PI
A Splash of Color in Your Lab
CellDrop is available in two colors: Leaf Green and Arctic White.
CellDrop results include a wide range of application-specific metrics for each cell sample. Data is clearly displayed on-screen and auto-saved to a large onboard hard drive. Metrics include:
A wide range of graph types are available to gain additional sample insight. Overlay multiple samples from the same session or from the data archive for powerful data visualization.
The convenient dilution calculator automatically calculates target dilution volumes of cell culture and buffer based on each cell count. Dilution guidance is displayed prominently on-screen and in printed reports for easy sample processing.
CellDrop EasyApps software is designed by life scientists, for life scientists. The system features a high definition, 7″ touchscreen and pre-installed apps for a range of common applications.
Additional apps for accounts, data, and other utilities contribute to the system’s easy-to-use interface.
DeNovix CellDrop Series instruments are stand-alone systems equipped with intuitive, easy-to-use apps for automatic cell counting and viability analysis.
Export results and images to USB, email, network folders, or printers. Export formats include PDF reports, .csv files, and .png files.
Setting the focus on the CellDrop is easy. Because of the CellDrop’s fixed sample surfaces, adjusting focus is not often needed once it has been set. However, the software is also equipped with Autofocus. Just press the Auto button in the focus menu to automatically adjust to the correct focus.
Cell / Nuclei Size Histograms allow easy gating for non-target cells or cell debris. Simply drag the slider to set the cell size of interest and view the results in real time. Results are instantly re-calculated excluding all debris or cells that fall outside of the defined size range
When using the dedicated GFP App, users can gate cells by fluorescence intensity as well as size. The intensity histogram displays the number of cells counted at each GFP intensity level allowing the exclusion of non-GFP expressing cells or low expressing cells to be excluded from analysis.
All CellDrop Count Apps use proprietary declustering algorithms developed by DeNovix. Complex samples of regular or irregular cells over a wide range of cell density can be rapidly and accurately counted. Analysis of cluster size and frequency can be performed and graphically displayed.
For cells that are elongated or irregularly shaped, enable Irregular Cell Mode from the Protocol Settings or the Optimize Setting button on the results screen. This is ideal for cells that are not round when trypsinized, such as fibroblasts or epithelial cells with a high degree of structure.
Irregular Cell Mode is also used to identify irregularly shaped isolated nuclei, such as smooth muscle nuclei from heart tissue.
A full installation and qualification (IQ/OQ) package is available for the CellDrop Automated Cell Counter.
The performance verification slide is a slide with beads fixed on the surface and is designed for assessing the accuracy and precision of a CellDrop Automated Cell Counter. Each slide includes a factory-certified value for the number of beads on the slide.